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Individuals with a history of any digestive, cardiovascular, or metabolic diseases which would interfere with glutathione absorption or metabolism, knowingly pregnant and nursing females, and individuals taking daily oral prescription medication were excluded from the study to minimize confounding factors which could influence glutathione levels
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dose spacing or serum-level monitoring may be necessary
It was established that carboxyethylpyrrole (a LPO product) induces retinal infiltration of macrophages, a pathological process that is blocked by the immunosuppressive therapy of CD4+ T cells (specifically Th1 and Th17 cells) (57)
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