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Degradation is one of the most common and least suspected causes of reduced effectiveness

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Common Causes Histamine Intolerance: Genetic factors Digestive issues that damage the intestinal lining Hormonal shifts during pregnancy, perimenopause, and menopause Certain medications (NSAIDS, antidepressants, antihistamines) Chronic health conditions the IBD Eating too many histamine-rich foods (pineapples, tomatoes, cheese, etc) The build up of histamines triggers an immune response and increases inflammation

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The practical tradeoffs between the two methods come down to time, customization, and cost

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Potential side effects to be aware of include: Bruising or tenderness where the IV catheter is placed

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