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Systematic reviews and meta-analyses report modest improvements in fasting glucose, insulin sensitivity, lipid markers, and blood pressure in some populations, particularly at doses between 24g per day.8 32 33 34 Overall, the magnitude of these effects tends to be modest.7 12 40 People with polycystic ovary syndrome (PCOS) Many of inositols studied benefits in PCOS appear to stem from its effects on insulin signaling, which plays a central role in the conditions metabolic and reproductive features