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This hormone is released by the gut in response to food intake and plays several important roles in glucose regulation
It contains compounds that your body may use to produce sex hormones, such as estrogen and testosterone ( A 12-week study found that supplementing with 600 mg of fenugreek extract daily improved sexual function and increased testosterone levels in 120 middle-aged and older males ( However, its unknown whether this increase in testosterone is clinically significant
For most patients, starting current options like semaglutide or tirzepatide makes more sense than waiting 18+ months for retatrutide
In head-to-head clinical trials (SURMOUNT-5), tirzepatide produced greater average weight loss (20.2% vs 13.7%)
Lower concentrations mean larger injection volumes, which can be easier to measure accurately with standard insulin syringes
