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The peptide works best when integrated with appropriate nutrition rather than as a standalone intervention
To put this in perspective with actual patient impact, here is how the percentage milestones break down for tirzepatide 15mg in SURMOUNT-1: The difference is not subtle
They have well established adverse effects, such as respiratory depression, sedation, and constipation, which can generate or exacerbate HE, and so should be used with caution
Give them a reason to stay for weight loss too
10.3389/fcell.2022.821014 52 KimJ.XuM.XoR.MatesA.WilsonG
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