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G protein-biased agonists represent one promising direction

It is also contraindicated in acute metabolic acidosis, severe hepatic impairment, or conditions predisposing to tissue hypoxia (such as decompensated heart failure, acute myocardial infarction, or severe respiratory disease)

Nevertheless, in rare cases, mild side effects such as nausea, headache or dizziness may occur

To investigate the neuroprotective effects of LipRSV, oxidative stress markers were quantified in these brain regions

[12] [13] Rare but serious risks include pancreatitis and, theoretically, thyroid C-cell tumours (based on animal studies)