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Most Contrave side effects start within the first few days or weeks and often improve as your body adjusts
This helps lower blood sugar spikes, reduce cravings, and shift your metabolism toward burning fat more efficiently
On the other hand, a Japanese single-center, open-label trial compared sitagliptin at suboptimal dosage with glimepiride in a cohort of 20 diabetic patients with ultrasound evidence of fatty liver: after 24 weeks of treatment, in the sitagliptin group but not in the glimepiride group, there was a significant reduction in intrahepatic lipid content and total body fat mass on H-MRS and DEXA despite a similar decrease in HbA1c [92]
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