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Intranasal administration of Ex-4 at a dose of 0.5 g/kg daily for 7 days before MCAO in mice, rather than intraperitoneal administration at an equivalent dose, exerted neuroprotective effect by reducing infarct volume and neurological deficits which were blocked by knocking down GLP-1 receptor with shRNA (136)
Seniors cant get these drugs because Medicare is barred by law from covering them for obesity
Generally well-tolerated with minimal reports of mild headaches or nasal irritation
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