What the Evidence Actually Says This is the section most pages ranking for this term avoid, and it is the one that matters clinically
El-Rashidy, O
Glutathione in Treating Mold Toxicity Glutathione is a compound our bodies make and is a powerful antioxidant that supports immune system function and promotes detoxification
What they found (summary): MC1R: melanogenesis, pigmentation, anti-inflammation MC2R: ACTH receptor in the adrenals (Melanotan II does not act) MC3R: energy, cardiovascular function, anti-inflammation MC4R: appetite (central control), sexual function, autonomic regulation MC5R: exocrine glands (sebaceous, lacrimal, salivary) Mutations in MC4R are the most common monogenic cause of obesity in humans Why it matters: Cones review article is the reference article for all of melanocortin pharmacology
Circ Res 119:330340 Fuster V, Moreno PR, Fayad ZA, Corti R, Badimon JJ (2005) Atherothrombosis and high-risk plaque: part I: evolving concepts