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The GLP-1 analogs, semaglutide and liraglutide, delay the progression of atherosclerosis by regulating inflammatory pathways in low-density lipoprotein receptor-deficient (LDLr -/- ) and apolipoprotein E-deficient (ApoE -/- ) mice [16]

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The other lipid metabolism-related genes, including HAD, ACOX3, CD36, ATGL and HSL , remained unchanged in the livers and muscles of the two groups in the two states

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In 2012, a once-weekly version called Bydureon was approved

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