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A randomized, double-blind, phase 2b proof-of-concept clinical trial in early alzheimers disease with lecanemab, an anti-abeta protofibril antibody
This is consistent with the glucagon receptor activation driving increased sympathetic tone and thermogenesis
The RAW files were uploaded to Integrated Proteomics Pipeline (IP2) and searched using the ProLuCID algorithm (publicly available at using a reverse concatenated, non-redundant version of the Mouse UniProt database (release 2017)
Both studies showed no increase in the adverse effects of combining these two medication groups [65]
Hinz M, Krappmann D, Eichten A, Heder A, Scheidereit C, Strauss M
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