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Accordingly, many studies reported dietary nutrients or phytochemicals that present the potential to restore GSTP1 expression ( CONCLUSIVE REMARKS Considering that the discrimination power of serum prostate-specific antigen (PSA) measurement between benign and malignant tumor cells is currently under controversial discussion, the best and the most promising epigenetic marker for prostate cancer detection is the hypermethylation of GSTP1

Replacing the phenyl ring with a heterocyclic moiety was also well tolerated and resulted in potent hits (cluster-2)

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