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In the cardiovascular system, incretins have been recently associated to the increase of endogenous antioxidant defenses, inhibition of cardiomyocyte apoptosis, attenuation of endothelial inflammation and dysfunction [55]
The injection is typically given in areas such as the abdomen, thigh, or upper arm, and can be done at home after proper instruction from a healthcare provider
6.8 % of the patients treated with Semaglutide discontinued it in perpetuity due to adverse reactions
The abdominal area typically has abundant subcutaneous tissue for GLP-1 medications
The FDA-approved dosing schedule includes gradual titration specifically to improve gastrointestinal tolerability
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