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To make things worse is the fact that, with current traditional treatments, there is little chance of fully reversing chronic fatigue

The main practical cautions are its blue-green color (which can tint formulations) and formulation incompatibility with certain other actives notably strong direct-acid vitamin C and high concentrations of exfoliating acids, which can destabilize the copper complex

"Pharmacokinetics, distribution, metabolism, and excretion of body-protective compound 157, a potential drug for treating various wounds, in rats and dogs"

Saponins seem to inhibit oxidative stress, inflammation and growth of cancer cells, and promote their self-destruction (apoptosis) in cell studies

In certain cases, other medications, including some antidepressants, may be prescribed off-label