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excess is renally excreted, though very high levels can cause dermatologic or metabolic effects
GLP-1 receptors are found not just in the gut and pancreas, but also in the lungs, brain, ovaries, testes, and uterus
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Es as como a medida que progresa la historia natural de la enfermedad, incluso desde la prediabetes, se pierden los efectos insulinotrpicos de esta hormona, lo que es responsable en parte de la hiperglucemia y la disfuncin de la CBP al no poder cumplir el efecto incretina, considerndose una marca distintiva de la enfermedad 49
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