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It involves molecular interactions that change red blood cells shape
Fluoxetine also decreased the activity of 17-beta-hydroxysteroid dehydrogenase type 6 (17-HSD6), a steroidogenesis-related enzyme, and lowered serum testosterone levels by affecting the steroidogenic capacity of Leydig cells
Thus, it can be hypothesized that the critical importance of Ca 2+ signaling in eryptosis is linked to the expulsion of the nucleus and the organelles (primarily mitochondria) in precursors of erythrocytes during erythropoiesis
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