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Harper JW, Ordureau A, Heo JM
Greater weight loss potential The SURMOUNT-5 trial, published in NEJM in 2025, directly compared tirzepatide against semaglutide in adults with obesity (without diabetes)
They work by mimicking the hormone GLP-1, helping to regulate blood sugar while dramatically reducing appetite
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In the same line, Fujita et al described a patient on chronic hydrocortisone who manifested symptoms of hypocortisolism after the start of exenatide therapy [33]
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