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First RCT: Semaglutide in Alcohol Use Disorder + Obesity A potential game-changer beyond glycemic control & weight loss A newly published randomized controlled trial in The Lancet provides the first robust clinical evidence that semaglutide may help reduce alcohol consumption in patients with alcohol use disorder (AUD) and obesity
In general, a plan of 5-6 injections within 6-8 weeks is recommended
Continued weekly subcutaneous semaglutide can help maintain weight loss and metabolic benefits, and this ongoing treatment is often necessary for long-term success
But nearly 40% of users in that same study saw negligible benefit because they approached dosing like a vitamin supplement rather than a metabolic intervention
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