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More serious but less common adverse effects require clinical vigilance
Cytokinetic resistance in acute leukemia: recombinant human granulocyte colony-stimulating factor, granulocyte macrophage colony-stimulating factor, interleukin-3 and stem cell factor effects in vitro and clinical trials with granulocyte macrophage colony stimulating factor
In light of the on-target and off-target liabilities outlined above, we recommend a development path that prioritizes separation of lesion efficacy from systemic exposure
Irn J Reprod Med 2012;10(2):77-82
Di Pietro G, LA Magno V, Rios-Santos F (2010) Glutathione S-transferases: an overview in cancer research
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