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(Frontiers in Pharmacology, 2022) reported pharmacokinetics and tissue distribution in rats and dogs, including a rapid plasma half-life under 30 minutes after IM or IV dosing

Epithalon is a synthetic tetrapeptide, a four amino acid peptid, that mirrors Epithalamin, the naturally occurring polypeptide secreted in the epithalamium-epiphyseal region of the brain (the pineal gland area)

The main concerns are quality control and lack of long-term human data

ATP6AP1 deficiency causes an immunodeficiency with hepatopathy, cognitive impairment and abnormal protein glycosylation

Glutathione actually works synergistically with Vitamin C they recycle each other