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Who Should Not Take Tirzepatide
This finding in women is consistent with prior reports suggesting that GLP-1 RAs may produce more pronounced weight loss and glycemic improvements in female people, potentially due to sex-specific differences in GLP-1 receptor expression, pharmacodynamics, or hormonal interactions [21]
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At week 52, using the treatment-policy estimand analysis, however, the oral semaglutide group experienced significantly greater decreases in A1C compared with both the liraglutide and placebo groups
