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Factors That Affect How Long B12 Injections Last Several factors may influence how long the effects of a B12 injection last in your system, potentially explaining why some patients require more frequent injections than others, even with the same underlying condition
How to Administer Vitamin B12 Injections Vitamin B12 injections are usually administered intramuscularly, meaning the injection is given directly into a muscle
However, indirect factorsincluding altered gastric emptying, reduced dietary intake, and concurrent metformin usemay influence B12 status in patients taking this medication
If you have pre-existing deficiencies, addressing them before starting aggressive weight loss improves outcomes and reduces complication risk
Some studies show a small increase in resting metabolic rate, possibly mediated by improved insulin sensitivity and reduced lipotoxicity in tissues
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