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showed that mtDNA mutations were also found in T21 brain tissues (Coskun and Busciglio 2012)

Daily use builds caffeine tolerance, which reduces both the energy boost and the fat-oxidation effect over time

Controversies over subungual tumors in incontinentia pigmenti

L-carnitine supplementation improves serum lipid parametersincluding total cholesterol (TC), triglycerides (TG), and low-density lipoprotein (LDL) in NASH patients (3638)

For healthcare systems and policymakers, the evidence supports cautious optimism tempered by realistic acknowledgment of current limitations and the need for comprehensive approaches that address pharmacological efficacy, access, sustainability, and equity concerns