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Clinical Trial Outcomes In EMPA-REG, empagliflozin users lost 23 kg over 2452 weeks
The slowed gastric emptying reduces the rate at which stomach contents move into the small intestine, which lowers postprandial glucose peaks but can increase sensations of early satiety, bloating, and nausea
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The amylin pathway regulates satiety through different brain regions and different molecular cascades
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