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140 Whereas the continuous supply of FeS clusters by NFS1 also prevented the iron-starvation response from being triggered in lung adenocarcinomas, NFS1 suppression was shown to predispose cancer cells to ferroptosis

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Ti mehanizmi dosad su promatrani iskljuivo u pretklinikim modelima i zahtijevaju daljnja istraivanja kako bi se potvrdila njihova primjenjivost na humane sustave

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