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The therapeutic rationale for developing a long-acting PYY analog for the treatment of Prader-Willi Syndrome (PWS) is grounded in the role of PYY as a gut-derived hormone that is involved in the regulation of appetite and satiety

If a dose is missed, product-specific guidance applies: For semaglutide (Ozempic, Wegovy) : Administer within 5 days of the missed dose, then resume the regular schedule

With the 180-day exclusivity, it enjoys six months of duopoly pricing that can generate 60-80% of the products total generic market profit

Amphetamines, by contrast, can increase heart rate and blood pressure, particularly at higher doses

The mechanisms make sense