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doi: 10.1155/2015/576726 117

Struggling to lose weight despite eating well and staying active is more common than most people think

While the SURMOUNT trials showed dose-dependent efficacy starting at 5 mg, some individuals may achieve better results at higher maintenance doses, with therapeutic effects typically becoming more pronounced as dosing increases

Why it's challenging: Growth hormone is released in pulses throughout the day, with the highest levels occurring during deep sleep

A 2022 study published in The Journal of Clinical Endocrinology & Metabolism found that patients with type 2 diabetes using GLP-1 medications reported lower levels of depression and anxiety symptoms (Lee et al., 2022)