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Drugs molecules that contain a primary amino (NH 2 ) group undergo oxidative deamination (Figure 5) in which the amino group is directly removed and oxygen is incorporated in drug molecules
Programmed cell death in hepatic fibrosis: current and perspectives
Stringer JM, Alesi LR, Winship AL, Hutt KJ
,[21] is more stable in blood plasma than GSH, and enters the cells directly, where it is converted to reduced glutathione by the abundant cytoplasm thioesterases
The take-home is that even in well-managed cohorts on daily oral vitamin B12, a meaningful percentage of patients still end up deficient
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