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Who likely does not need it: People without thyroid conditions and no thyroid medication use
J Diabetes Complications 2022;36:108255.ArticlePubMed 92
However, whilst there is no official prohibition against combining these medications, healthcare professionals must carefully consider the indirect metabolic effects that may arise from their concurrent use
the full report contains the complete analysis
Summary of evidence Randomized clinical trials such as CREDENCE [52](Canagliflozin and Renal Events in Diabetes with Established Nephropathy Clinical Evaluation) and DAPA-CKD [53, 54] (Dapagliflozin and Prevention of Adverse Outcomes in Chronic Kidney Disease) evaluated sodium-glucose cotransporter 2 (SGLT2) inhibitors in patients with T2DM and DKD, proving the reduction of renal outcomes, such as progression to advanced kidney disease, the need for dialysis and renal death
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