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Early-phase insomnia linked to semaglutide typically manifests as delayed sleep onset (difficulty falling asleep) rather than early morning awakening

This means it can help the body if there is too little nitric oxide, but it also has the potential to step in if levels become dangerously high

Tirzepatide should be discontinued promptly if pancreatitis is suspected and not restarted if pancreatitis is confirmed

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Patients often see a reduction in fasting blood glucose levels and HbA1c (a measure of long-term blood sugar control) over the initial weeks and months