doi: 10.3389/fphar.2022.812362 44 EnglerHDawilsLHovesSKurthSStevensonJRSchauensteinKet al
References 1 Wu, G., Fang, Y.-Z., Yang, S., Lupton, J
Generally, large ions with low charge density (e.g., Ba 2+ ) are strong chaotropic agents (substances capable of breaking the hydrogen bonding network between water molecules) and they can significant hinder hydrophobic interactions, whereas small ions with high charge density (e.g., PO 4 3- ) are highly anti-chaotropic and can substantially promote hydrophobic interactions5
Unlike many peptides, BPC 157 is unique due to its remarkable stability and widespread cytoprotective properties
Various chemical inducers of the NRF2 activity have been identified in the last two decades, but several of these compounds still have significant drawbacks associated to their clinical potential: suboptimal pharmacokinetics (concentration vs