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Eosinophilic crystals have been described in intrahepatic bile ducts and gallbladder of different laboratory mice strains, and some of these crystals have been shown to contain chitinase-like proteins confirmed by immunohistochemistry for Ym1 protein (now Chi313) (Ward et al

Sikiric et al., 2020b), this provides overcoming (Seiwerth et al., 2018) of the technical and practical limitations now presented as shortage in the corresponding standard angiogenic growth factors applicability and diverse delivery and carrier systems (see Practical Application as Support )

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Matsumura, S