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Tirzepatide (Mounjaro, Zepbound) is a novel glucose-dependent insulinotropic polypeptide (GIP) and glucagon-like peptide-1 (GLP-1) receptor agonist approved by the FDA for type 2 diabetes management and chronic weight management in adults with obesity (BMI 30 kg/m) or overweight (BMI 27 kg/m) with at least one weight-related comorbidity

By stimulating insulin secretion and suppressing glucagon release, liraglutide aids in better glycemic control while indirectly promoting weight loss

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The Novo Nordisk Canada Wegovy consumer information notes that nausea, vomiting, and diarrhea can cause dehydration and says drinking fluids is important, especially for people with kidney problems

For someone using semaglutide for weight management, the appetite suppression weakens