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Intravenous (IV) glutathione is limited by an extremely short half-life in the plasma, and it cannot cross cell membranes intact, but must be broken down and resynthesized within the cell
Tumor necrosis factor-alpha antibody for maintenance of remission in Crohns disease
Their presence in these regions is not incidental
Compared to classical gastroprotective peptides such as sucralfate or proton pump inhibitors (PPIs), it acts via a completely different pathway: restoration of mucosal microcirculation rather than acid reduction or formation of a mechanical protective layer
Pyke C, Heller RS, Kirk RK, Orskov C, Reedtz-Runge S, Kaastrup P, Hvelplund A, Bardram L, Calatayud D, Knudsen LB
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