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Thanks to their expanded interface with the target protein, peptide PROTACs demonstrate superior potency, higher selectivity, and reduced toxicity compared to low molecular weight compounds, especially when targeting proteins lacking well-defined binding pockets (Kargbo, 2019)
doi:10.2337/dc22-S002 2
Etc, etc, etc
As Zepbound and Wegovy are FDA-approved for weight loss and management, they are considered the best options out of all of the Semaglutide GLP-1 and Tirzepatide formulations available
Diabetes Care 27 , 155161 (2004)
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