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Despite being mechanistically different, pyroptosis, ferroptosis, apoptosis, necroptosis act synergistically via shared signaling nodes in DKD, with mitochondrial ROS (mtROS) and serving as a pivotal common mediator (112, 176, 207)

Researchers are exploring how GLP-1 receptor agonists interact synergistically with medication-assisted treatment, cognitive-behavioral therapy, and neuromodulation techniques such as transcranial magnetic stimulation

*Correspondence: Ze Wang, [email protected] Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

These neurons may play a role in behaviors such as drinking