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The solvent in step-a) and step-b) wherever necessary is selected from hydrocarbon solvents, ether solvents, ester solvents, polar-aprotic solvents, chloro solvents, ketone solvents, nitrile solvents, water and the like or mixtures thereof

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Reductions in inflammatory biomarkers have been documented in several clinical studies, although the precise contribution of microbiome-mediated pathways remains under investigation

Fungi like Candida and Aspergillus form drug-resistant biofilms, where extracellular matrices limit antifungal penetration and induce dormant persister cells (Morelli et al., 2021