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At non-toxic concentrations of 1 to 10 nM, the peptide stimulates in preclinical models both the synthesis and the breakdown of collagen and glycosaminoglycans such as dermatan and chondroitin sulfate as well as decorin, and it modulates matrix metalloproteinases together with their inhibitors TIMP-1 and TIMP-2

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Initial procedure based on standard treatment of 1-2 pellets (lab dependent)