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These stressors can disrupt normal metabolic flux, potentially leading to the accumulation of toxic intermediates within cells and altering cellular metabolic homeostasis (21)
Doses of pyridoxine as low as 5-10 mg can antagonize levodopas effect if carbidopa is not present, so caution is warranted and any supplemental B beyond the nutritional dose should be under medical guidance
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ROS can damage DNA, proteins, and lipids and activate a variety of inflammatory pathways, all of which contribute to psoriatic inflammation [4, 5]
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