Studies have shown that significant concentrations of lixisenatide were found in the brain of mice 30 minutes and 3 hours after intraperitoneal injection, suggesting that lixisenatide could cross the BBB (125)
PSMA I&T can be used for SPECT/CT imaging and radionuclide studies in triple-negative breast cancer and prostate cancer (PCa)
Tongue edema was reported rarely ( 1% of patients
Developing a discontinuation plan should include establishing baseline measurements (weight, waist circumference, metabolic parameters), setting realistic expectations about weight maintenance challenges, creating a detailed lifestyle modification plan with specific, measurable goals, scheduling regular follow-up appointments (initially monthly, then quarterly), identifying triggers for earlier intervention if weight regain occurs, and discussing alternative pharmacological options if needed
At 9 and 12 months, previous liraglutide users continued to have a lesser weight loss than medication-naive adults