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Sigma, Saint Louis, Missouri) Oxidative stress was assessed by the quantification of protein carbonyls and MDA using Protein Carbonyl Colorimetric and TBARS Assay Kits, respectively (Cayman Chemical, Ann Arbor, MI)
Effect of one-year vitamin C- and E-supplementation on cerebrospinal fluid oxidation parameters and clinical course in Alzheimer's disease
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muciniphila were associated with the accumulation of nicotinamide in the CNS, which was further supported by an improvement in motor symptoms and gene expression patterns in the spinal cord of Sod 1-Tg mice following systemic supplementation with nicotinamide
A controlled study by Laferrere et al
