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Low testosterone and poor sperm count are commonly linked to obesity and excess weight
In addition, L-2-HG accumulation in an acidic pH environment has been reported to result in HIF-1 stabilization in normoxia 91 (Fig
Notably, T2DM is closely associated with various neurodegenerative conditions ranging from mild cognitive impairment (MCI) to dementia
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thus, there is an urgent need for an effective intervention to reset the circadian clock and prevent metabolic syndrome and metabolic syndrome-induced cancers
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