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Patients on blood thinners BPC-157 has demonstrated interactions with the coagulation system in animal studies

More serious complications are rare but could include infiltration (IV fluid leaking into surrounding tissue), phlebitis (inflammation of the vein), infection (extremely rare with proper technique), or allergic reactions to ingredients

Among research peptides, ARA-290 occupies a distinctive position: it has more human clinical trial data than most compounds in the peptide space, including Phase 2 randomized controlled trials for sarcoidosis-associated small fiber neuropathy and diabetic neuropathy, and it holds both FDA Orphan Drug and Fast Track designations for neuropathic pain in sarcoidosis

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Finally, in addition to the local action within the hippocampus, new neurons could be preferentially targeted by afferents originating from many brain regions