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2a, b) highlights the importance of the bioavailability of cysteine to enable cells to adapt to metabolically challenging conditions, as well as mediating cancer cell survival, tumour growth, metastases formation, resistance to therapy and disease recurrence
PubMed PMID: 19289567
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Based on simulations, the average concentration at day 10 was 66% of exposure at steady state, and the accumulation ratio was estimated to be 12.6 from day 1 to steady state (computed via simulations including inter-individual variability and inter-occasion variability)
Dispose of the used needle in a sharps container immediately after use
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