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(2024, CNS Neuroscience & Therapeutics ) confirmed ARA-290 provided neuroprotective effects in a mouse MCAO (middle cerebral artery occlusion) model comparable to full-length EPO, significantly reducing neuronal apoptosis and inflammatory cytokines, confirmed to act via CR without stimulating erythropoiesis Blood-brain barrier (BBB) penetration confirmed in pre-clinical studies
A reduo da produo de cido ltico outro benefcio observado: o que diminui a sensao de queimao nos msculos durante o exerccio
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Discontinuation and reinitiation of SGLT-2 inhibitors and GLP-1R agonists in patients with type 2 diabetes: a nationwide study from 2013 to 2021
However, dehydration from common gastrointestinal side effects (nausea, vomiting, diarrhoea) may theoretically increase kidney stone risk by concentrating urine
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