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29 GLP-1, an endocrine hormone, is secreted by enteroendocrine L-cells located in the distal jejunum, ileum, and colon in response to nutrient ingestion and neuroendocrine stimulation

Do not use Mounjaro if you: Have a serious allergic reaction to tirzepatide, Mounjaro, Zepbound, or any of the inactive ingredients contained in Mounjaro prefilled pens, kwikpens, or vials (see below for a list of ingredients) Or any of your family members have ever had a type of thyroid cancer called medullary thyroid carcinoma (MTC) Have an endocrine system condition called Multiple Endocrine Neoplasia syndrome type 2 (MEN 2) Before receiving Before receiving or using Mounjaro , tell your healthcare provider about all your medical conditions, including if you have: Have or have had problems with your pancreas Have severe problems with your stomach, such as slowed emptying of your stomach (gastroparesis) or problems with digesting food Have a history of diabetic retinopathy Are scheduled to have surgery or other procedures that use anesthesia or deep sleepiness (deep sedation) Are pregnant or plan to become pregnant Are breastfeeding or plan to breastfeed