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Materials and methods Animal experiments C57BL/6J aged (20 months) male mice and mast cell deficient c-Kit wsh /cKit wsh mice (12 months) were housed in a specific pathogen-free facility (light cycle 12/12 h light/dark)
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JAMA Oncol
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Activation of nuclear factor-B (NF-B) induces transcription of target genes that primarily encode survival proteins (e.g., cellular FLICE-like inhibitory protein and inhibitor of apoptosis proteins) via formation of the complex I signalosome after binding to TNF receptor-1
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