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Common adverse effects include gastrointestinal symptoms, particularly nausea (30-50% of patients), vomiting, diarrhea, and constipation

Yet, as I have observed in my patients, real-world outcomes of using these weekly injectables reveal challenges: from gastrointestinal side effects and nutritional deficiencies to muscle and bone loss, adherence issues, and high treatment costs

Terasaki, M

Using Big Data to Emulate a Target Trial When a Randomized Trial Is Not Available

Additional CD1a low langerin neg/low cells were also identified, and combined with differential expression of CD11c or CD1c, were termed epidermal dendritic cells (Epi-cDC2s) 24 or LC2 25 , respectively