It contains polysulfated glycosaminoglycan, which helps protect cartilage, limit further joint damage, and improve the quality of joint fluid
One of the open questions in the field is, whether iron overload is just a consequence of increased transfusion frequency, which is a well-known measure of disease severity, which would explain the worse prognosis, or, whether iron overload per se has a negative impact on the course of the disease
Mood and Mind Support: Beyond energy, B-12 contributes to mood regulation and cognitive function
Hydration: Adequate hydration reduces constipation risk in patients who experience reduced fluid intake alongside appetite suppression
Consistency and personal health status also play an important role in the timeline