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Journal of Investigative Medicine , 70(1), 513

In the U.S., Japan and Europe, Novos own patent table lists active-ingredient protection for Ozempic, Wegovy and Rybelsus running to 2032 in the U.S

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More generally, doses of peptide-antibody fusions for testing in vivo stability of the GLP-1 activity were adjusted based on their human GLP-1R potency and material availability